Cat. No.
MABL-570
Application
ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
3G7
From
Recombinant Antibody
Specificity
Binds specifically to the 2e loop of the human C3a receptor, residues 185-193.
Alternative Names
Complement component receptor 1; C3AR1
UniProt
Q16581
Immunogen
The 2e loop of the C3a receptor.
Application Notes
This scFv antibody binds to the 2e loop of the human C3a receptor, a G protein- coupled receptor stimulating chemotaxis, superoxide anion generation and granule enzyme release.
Antibody First Published
Hawlisch et al. 2001 Site-specific anti-C3a receptor single-chain antibodies selectied by differential panning on cellulose sheets. Analytica Biochemistry 2001; 293(1)：142-145 PMID：11373092
Note on publication
Describes the selection of scFv fragments with specificity for the C3a receptor from phage-display libraries.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
