Cat. No.
MABL-612
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Neisseria meningitidis serogroup c
Clone No.
4-2-C (7H9-4)
From
Recombinant Antibody
Specificity
This antibody is specific for capsular polysaccharides of Neisseria meningitidis serogroup C, showing no reaction against encapsulated serogroup B organisms.
Alternative Names
Neisseria meningitidis serogroup C capsular polysaccharide; NmC
UniProt
Immunogen
The original antibody was generated by immunizing mice with whole encapsulated N. meningitidis.
Application Notes
This antibody can be used for the identification of capsular polysaccharide of Neisseria meningitidis serogroup C using an ELISA. The cross reactivity of this antibody towards various serogroups of N. meningitidis was checked using ELISA (PMID: 15589322). This antibody can also be used in a whole cell ELISA at a 1: 2000 dilution for detection of serogroup C (PMID: 12721942)
Antibody First Published
Berry et al. Molecular analysis of monoclonal antibodies to group variant capsular polysaccharide of Neisseria meningitidis: recurrent heavy chains and alternative light chain partners. Mol Immunol. 2005 Feb; 42(3): 335–344. PMID:15589322
Note on publication
Describes the generation of antibodies against serogroup B and C of Neisseria meningitidis.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
