Key features and details | |
Cat. No. | MABL-2107 |
Name | Anti-IL-8 mAbs |
Clone No. | AFD- 6E6 (I8-60) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibit, neutralize, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human IL-8, which is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. |
Alternative Name | IL8; Interleukin-8; CXCL8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor; CGMCC No 1249 |
UniProt | P10145 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with recombinant human IL- 8. |
Application Notes | The binding specificity of this antibody for human IL-8 was determined using ELISA. The microporous chamber chemotaxis assay was used to detect the inhibitory effect of this antibody on the chemotactic activity of IL-8. It was reported that 1ug/ml of this antibody can significantly inhibit the chemotactic activity of IL-8 (CN1309738). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
