CAT.NO | MBA-0061 |
NAME | Recombinant Anti-Neural/glial antigen 2 (NG2) antibody |
Isotype and Format | Mouse IgG2a, Kappa |
Clone Number | 9.2.27 |
Alternative Name(s) of Target | CSPG4; melanoma chondroitin sulfate proteoglycan; MCSP; CSP |
UniProt Accession Number of Target Protein | Q6UVK1 |
Published Application(s) | IP,FC,IF |
Published Species Reactivity | Human |
Immunogen | The original antibody was generated by immunizing Balb/c mice with a 4M urea extract derived from human melanoma cells (M14). |
Specificity | This antibody is specific for human neural/glial antigen 2. |
Application Notes | This antibody binds to melanoma-associated chondroitin sulphate proteoglycan, which stabilises cell-substratum interactions during the early stages of melanoma spreading. |
Antibody First Published in | Morgan et al. Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma. 1981;1(1):27-36. PMID:6208119 |
Note on publication | The original publication details the production and characterization of a monoclonal antibody which recognizes a 240K dalton glycoprotein specific to melanoma cells. |
Size | 200 μg Purified antibody. Purification |
Purification | Protein A affinity purified |
Supplied In | PBS with 0.02% Proclin 300 |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
Concentration | 1 mg/ml. |