| CAT.NO | MBA-0069 |
| NAME | Recombinant Anti-Prion Protein antibody |
| Isotype and Format | Mouse IgG1, Fc Silent™, Kappa |
| Clone Number | 31C6 |
| Alternative Name(s) of Target | PrP; ASCR; CD-Antigen |
| UniProt Accession Number of Target Protein | P04156 |
| Published Application(s) | WB, ELISA, IHC |
| Published Species Reactivity | Human |
| Immunogen | Recombinant mouse scrapie-Prion protein residues 23-231 (rMoPrP23-231). |
| Specificity | Binds human PrP residues 143-149. |
| Application Notes | This is antibody recognises and binds to residues 143-149 of PrP. High Levels of PrP (Prion Protein) are found in the brain of humans and animals that are infected with transmissible spongiform encephalopathies such as Creutzfeld-Jakob disease (CJD), Gerstmann-Straussler disease in humans or bovine spongiform encephalopathy (BSE) in cattle. |
| Antibody First Published in | Kim et al. 2004 Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies. Virology. 2004; 320(1):40-51 PMID:15003861 |
| Note on publication | Describes the generation of several monoclonal antibodies against PrP by immunising PrP gene-ablated mice with the pathogenic form of PrP |
| Size | 200 μg Purified antibody. |
| Purification | Protein A affinity purified |
| Supplied In | PBS with 0.02% Proclin 300 |
| Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
| Concentration | 1 mg/ml. |
