CAT.NO | MBA-0073 |
NAME | Recombinant Anti-Cocaine antibody |
Isotype and Format | Human IgG1, Fc Silent™, Kappa |
Clone Number | GNC92H2 |
Alternative Name(s) of Target | Benzoylmethylecgonine |
UniProt Accession Number of Target Protein | |
Published Application(s) | ELISA |
Published Species Reactivity | n/a |
Immunogen | Benzoylecgonine-KLH conjugate. |
Specificity | Specifically binds to Benzoylmethylecgonine (Cocaine) with a Kd= 4E-7, which is 100-fold difference in Kd to the carboxylic acid metabolite Benzoylmethylecgonine |
Application Notes | This antibody binds to cocaine, a strong stimulant used clinically as a local analgesic and vasoconstrictor, as well as illegally as a recreational drug. |
Antibody First Published in | Larsen et al. 2001 Crystal Structure of a Cocaine-binding Antibody. Journal of Molecular Biology 2001; 311:9-15 PMID:11469854 |
Note on publication | Describes the generation and humanisation of a cocaine-binding antibody and the determination of its crystal structure. |
Size | 200 μg Purified antibody. |
Purification | Protein A affinity purified |
Supplied In | PBS with 0.02% Proclin 300 |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
Concentration | 1 mg/ml. |