| CAT.NO | MBA-0076 |
| NAME | Recombinant Anti-Neurotoxin AahII antibody |
| Isotype and Format | Mouse IgG1, Kappa |
| Clone Number | 4C1 |
| Alternative Name(s) of Target | neurotoxin II; alpha-mammal toxin II |
| UniProt Accession Number of Target Protein | P01484 |
| Published Application(s) | NTRL, ELISA |
| Published Species Reactivity | Androctonus australis hector |
| Immunogen | C-terminus of AahII |
| Specificity | This scFv binds specifically to the C-terminal region of the toxin. |
| Application Notes | This scFv binds to the C-terminus of the neurotoxin AahII, which binds and blocks sodium channels in a voltage-independent manner. The antibody neutralizes the toxin. |
| Antibody First Published in | Mousli et al. 1999 A recombinant single-chain antibody fragment that neutralizes toxin II from the venom of the scorpion Androctonus australis hector. FEBS Letters 1999; 442(2- 3):183-188 PMID:9928998 |
| Note on publication | Describes the engineering of an scFv that, similar to the whole antibody, neutralizes the activity of the neurotoxin. |
| Size | 200 μg Purified antibody. |
| Purification | Protein A affinity purified |
| Supplied In | PBS with 0.02% Proclin 300 |
| Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
| Concentration | 1 mg/ml. |
