Key features and details | |
Cat. No. | MABL-3149 |
Name | Anti-TSH mAbs |
Clone No. | AFD- 11A2A8B7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for TSH. Thyroid stimulating hormone is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone produced by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid. |
Alternative Name | CGMCNO.22318; Thyrotropin; Thyroid stimulating hormone; Thyrotropin subunit beta; Thyroid-stimulating hormone subunit beta; TSH-B; TSH-beta; Thyrotropin beta chain; INN: Thyrotropin alfa |
UniProt | P01222 |
Immunogen | The original antibody was generated by immunizing mice with TSH. |
Application Notes | The antibody specifically detected TSH by Western blot analysis. The antibody 11A2A8B7 and the commercial antibody TSH (TSH01 + TSH02) were used to stain pituitary tumors. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 11A2A8B7 was higher than the commercial antibody. The antibody and the commercially available antibody TSH (TSH01 + TSH02) were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN114149503A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
