Key features and details | |
Cat. No. | MABL-3150 |
Name | Anti-TSH mAbs |
Clone No. | AFD- TSM1.3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human thyroid stimulating hormone. Thyroid stimulating hormone is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone produced by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid. |
Alternative Name | Thyroid stimulating hormone; CHEBI:81567 |
UniProt | |
Immunogen | The original antibody was generated by immunizing balb/c mice with human TSH. |
Application Notes | The binding characterization of this antibody towards thyroid stimulating hormone was done using ELISA (Iba et al.,1995) |
Antibody First Published | Iba et al. A new system for the expression of recombinant antibody in mammalian cells. Biotechnology Letters volume 17, pages135–138(1995). |
Note on publication | Describes the generation of two plasmids to be used in the generation of a chimeric antibody containing variable regions derived from a mouse and constant regions derived from a human antibody chain. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |