| CAT.NO | MBA-0078 |
| NAME | Recombinant Anti-NgR1 antibody |
| Isotype and Format | Mouse IgG1, Kappa |
| Clone Number | M5 |
| Alternative Name(s) of Target | Nogo-66 Receptor |
| UniProt Accession Number of Target Protein | Q86UN2 |
| Published Application(s) | IP, WB, ELISA, FC |
| Published Species Reactivity | Rat, Human, Mouse |
| Immunogen | (His)6-tagged fragment of rat NgR1(amino acids 278-473). |
| Specificity | The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding). |
| Application Notes | The antibody binds specifically to residues 379-448 of NgR1, a member of the Nogo- 66 receptor family which inhibits axonal growth and sporulating in the CNS. |
| Antibody First Published in | Hofer et al. Chimeric Rabbit/Human Fab and IgG Specific for Members of the Nogo-66 Receptor Family Selected forSpecies Cross-Reactivity with an improved Phage Display Vector. Journal of Immunological Methods 2008; 318(1-2):75-87 PMID:17140598 |
| Note on publication | Describes the generation of two monoclonal rabbit antibodies against members of the Nogo-66 receptor family. |
| Size | 200 μg Purified antibody. |
| Purification | Protein A affinity purified |
| Supplied In | PBS with 0.02% Proclin 300 |
| Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
| Concentration | 1 mg/ml. |
