CAT.NO | MBA-0080 |
NAME | Recombinant Anti-ROBO-1 antibody |
Isotype and Format | Mouse IgG1, Kappa |
Clone Number | B2212A |
Alternative Name(s) of Target | Roundabout-1 |
UniProt Accession Number of Target Protein | Q9Y6N7 |
Published Application(s) | WB, ELISA |
Published Species Reactivity | Human |
Immunogen | Human recombinant ROBO-1. |
Specificity | The antibody binds specifically to the fn3-fibronectin domain of Human ROBO-1. |
Application Notes | This antibody binds to human ROBO-1, a receptor for SLIT1 and SLIT2. ROBO-1 is involved in axonal navigation, lung development, and cell migration. |
Antibody First Published in | Ito et al. Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research 2006; 12(11 Pt 1):3257- 64 PMID:16740745 |
Note on publication | Describes the generation of monoclonal antibodies against new cell surface targets for treatment of heptacellular carcinomas. |
Size | 200 μg Purified antibody. |
Purification | Protein A affinity purified |
Supplied In | PBS with 0.02% Proclin 300 |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
Concentration | 1 mg/ml. |